Sophie Brasselet Ph.D. - Homepage

Institut Fresnel, Marseille (France)

Publications

2026

4polar3D single molecule imaging of 3D orientation in dense actin networks using ratiometric polarization splitting
Charitra S Senthil Kumar, Cesar A Valades Cruz, Miguel Sison, Arturo G Vesga, Javier Rey-Barroso, Valentina Curcio, Luis A Alemán-Castañeda, Miguel A Alonso, Renaud Poincloux, Manos Mavrakis, Sophie Brasselet
Nature Communications 17, 4246 (2026)
The Achilles tendon enthesis rebuilds its mineralization front on reloading but retains a nanoscale imprint of unloading
ML Stammer, C Camy, M Frewein, I Silva Barreto, C Genovesio, M Eckermann, A Karimbana, K Iliopoulos, R Ranjan, N Wittig, T Fovet, T Brioche, A Chopard, M Burghammer, S Brasselet, H Birkedal, M Pithioux, S Roffino, TA Grünewald
arXiv 2608.23210 (2026)
Nanoscale rheological heterogeneity revealed by Single Particle orientation Tracking (SPoT) of ultrashort carbon nanotubes in brain tissue
Limeng Ruan, Hanna Manko, Quentin Gresil, Luis A Alemán-Castañeda, Morgane Meras, Finn L Sebastian, Ivo Calaresu, Benjamin Flavel, Jana Zaumseil, Laurent Groc, Sophie Brasselet, Marc Tondusson, Laurent Cognet
bioRxiv 2026.05. 04.721587 (2026)

2025

SMOLM-LFM: ratiometric single molecule orientation without polarizers
Arturo G Vesga, Luis Aleman-Castaneda, Hannah S Heil, Sam Daly, Ezra Bruggeman, Steven F Lee, Sophie Brasselet, Ricardo Henriques
bioRxiv 2025.11. 26.690201 (2025)
SPIN90 modulates the architecture of lamellipodial actin in an ARPC5L dependent fashion
LuYan Cao, Angika Basant, Miroslav Mladenov, Naoko Kogata, Antoine Jegou, Guillaume Romet-Lemonne, Sophie Brasselet, Manos Mavrakis, Michael Way
bioRxiv 2025.12. 01.691495 (2025)
Polarization MultiFocus Microscopy for volumetric super-resolution and orientation imaging of biofilaments
L Régnier, CV Rimoli, S Dey, FC Tsai, GA Orsi, S Brasselet, B Hajj
bioRxiv 2025.11. 19.687997 (2025)
Single-molecule orientation and localization microscopy
S. Brasselet and M. Lew
Nature Photonics https://doi.org/10.1038/s41566-025-01724-y (2025)
Genetically encoded reporters of actin filament organization in living cells and tissues
C. Silva Martins, F. Iv, S. Kumar Suman, T. C. Panagiotou, C. Sidor, M. Ruso-López, C. N. Plancke, S. Omi, M. Gomes, A. Llewellyn, S. Reddy Bandi, L. Ramond, F. Arbizzani, C. Vaz Rimoli, F. Schnorrer, F. Robin, A. Wilde, L. LeGoff, J.-D. Pedelacq, S. Cabantous, S.A. Rincon, C. Chandre, S. Brasselet, M. Mavrakis
⟨hal-04563732⟩ Biorxiv DOI: 10.1101/2024.04.26.591305 (2024)
Cell 188 (9), 2540 - 2559.e27 (2025) https://doi.org/10.1016/j.cell.2025.03.003
4polar3D : Single molecule 3D orientation imaging of dense actin networks using ratiometric polarization splitting
C. S. Senthil Kumar, C. A. Valades Cruz, M. Sison, A. G. Vesga, J. Rey-Barroso, V. Curcio, L. A. Alemán-Castañeda, M. A. Alonso, R. Poincloux, M. Mavrakis, S. Brasselet
Biorxiv DOI: 10.1101/2025.07.13.664601 (2025)
Preface to the special issue on advances in localization microscopy
S Brasselet, Y Shechtman, C Smith
Optics Communication577, 131362 (2025)

2024

Nonlinear Optics Through the Field Tensor Formalism
J. Duboisset, B. Boulanger, S. Brasselet, P. Segonds, J. Zyss
Laser and Photonics Reviews 2024, pp.2400411. doi.org/10.1002/lpor.202400411
Stokes-based analysis for the estimation of 3D dipolar emission
I. Herrera-Hernandez, L. Aleman-Castaneda, S. Brasselet, M. Alonso
J. Opt. Soc. Am. B 41(11), pp. 2134-2148 (2024) doi.org/10.1364/JOSAA.538706. Optica Open doi.org/10.1364/opticaopen.26502499.v1.
Vectorial phase retrieval in super-resolution polarization microscopy
R. Gutiérrez-Cuevas, L. Alemán-Castañeda, I. Herrera, S. Brasselet, M. Alonso
APL Photonics 9, 026106 (2024), doi.org/10.1063/5.0179906 (arXiv:2309.03611 2023)
Propagation-invariant optical meron lattices
D Marco, I Herrera, S Brasselet, MA Alonso
ACS Photonics 11(6) pp 2397-2405 (2024). doi.org/10.1021/acsphotonics.4c00292
Periodic skyrmionic textures via conformal cartographic projections
D. Marco, I. Herrera, S. Brasselet, and M. A. Alonso
APL Photonics 9, 110803 (2024). https://doi.org/10.1063/5.0230959. arxiv:2310.08964

2023

Influence of the excitation polarization on single molecule 3D orientation imaging
E. Munger, M. Sison and S. Brasselet
Opt. Communications (541), 129480 (2023). doi.org/10.1016/j.optcom.2023.129480
Polarization microscopy: from ensemble structural imaging to single molecule 3D orientation and localization microscopy. Minireview
S. Brasselet, M.A. Alonso
Optica 10 (11), 1486-1510 (2023) doi.org/10.1364/OPTICA.502119
Roadmap on bio-nano-photonics
Martina Elisena Recchia, Vikramdeep Singh, Nicole Slesiona, Martin Hörmann, Vasilis Petropoulos, Eleanor Munger, Eric Michele Fantuzzi, Ediz Herkert, Saurabh Borkar, Andrea Pruccoli, Rushikesh Laxmikant Burde, Thomas Deckert, Frank E Quintela Rodriguez, Jan Majer, Dominykas Gudavicius, Wolfgang Langbein, Peter Watson, Margherita Maiuri, Giulio Cerullo, Sophie Brasselet, Hervé Rigneault, Maria F Garcia-Parajo, Niek F van Hulst, Andreas Zumbusch, Daniele Brida, Filipo Troiani, Elisa Molinari, Steve Hood, Paola Borri
Journal of Optics 23(7) 073001 (2021). doi.org/10.1088/2040-8986/abff94

2022

Human septins in cells organize as octamer-based filaments mediating actin-membrane anchoring
C. Silva Martins, C. Taveneau, G. Castro-Linares, M. Baibakov, N. Buzhinsky, M. Eroles, V. Milanović, S. Omi, J.-D. Pedelacq, F. Iv, L. Bouillard, A. Llewellyn, M. Gomes, M. Belhabib, M. Kuzmić, P. Verdier-Pinard, S. Lee, A. Badache, S. Kumar, C. Chandre, S. Brasselet, F. Rico, O. Rossier, G. Koenderink, J. Wenger, S. Cabantous, and M. Mavrakis
J Cell Biol 222 (3): e202203016 (2022). https://doi.org/10.1083/jcb.202203016
In‐depth polarization resolved SHG microscopy in biological tissues using iterative wavefront optimization
D. Nuzhdin, E. G. Pendleton, E. B. Munger, L. J. Mortensen, S. Brasselet
Journal of Microscopy 1-16 (2022) https://doi.org/10.1111/jmi.13163
Unraveling the geometry of complex protein organizations by polarized fluorescence imaging, News and Notable
S Brasselet
Biophysical Journal 121 (22), 4242-4243. DOI: 10.1016/j.bpj.2022.09.022
Fluorescence polarization modulation super-resolution imaging provides refined dynamics orientation processes in biological samples
S Brasselet
News and Views, Light: Science & Applications 11 (1), 1-3. DOI: 10.1038/s41377-022-01018-w
Using fluorescent beads to emulate single fluorophores
L.A. Aleman-Castaneda, S.Y.-T. Feng, R. Gutierrez-Cuevas, I. Herrera, T.G. Brown, S. Brasselet, M.A. Alonso
JOSA A Vol. 39, Issue 12, pp. C167-C178 (2022) https://doi.org/10.1364/JOSAA.474837
Septin filament compaction into rings requires the anillin Mid2 and contractile ring constriction
Federica Arbizzani, Manos Mavrakis, Sophie Brasselet, Sergio A. Rincon and Anne Paoletti
Cell Rep 39, 110722, DOI: 10.1016/j.celrep.2022.110722 (2022).
DNA self-assembly of single molecules with deterministic position and orientation
A. Adamczyk, T. Huijben, M. Sison, A. di Luca, G. Chiarelli, S. Vanni, S. Brasselet, K. Mortensen, F. Stefani, M. Pilo-Pais, G. Acuna
ACS Nano 16, 10, 16924–16931. DOI: 10.1021/acsnano.2c06936
4polar-STORM polarized super-resolution imaging of actin filament organization in cells
C. Rimoli, C. Valades Cruz, V. Curcio, M. Mavrakis, S. Brasselet
Nat. Communications 13, 301 (2022). DOI: 10.1038/s41467-022-27966-w
Roadmap on Wavefront Shaping and deep imaging in complex media
S. Gigan, O. Katz, H. B. de Aguiar, A. Aubry, J Bertolotti, E. Bossy, D. Bouchet, J. Brake, S. Brasselet, Y. Bromberg, H. Cao, T. Chaigne, Z. Cheng, W. Choi, T. Čižmár, M. Cui, V.R. Curtis, H. Defienne , M. Hofer, R. Horisaki, R. Horstmeyer, N. Ji, A.K. LaViolette, J. Mertz, C. Moser, A. P. Mosk, N.C. Pégard, R. Piestun, S. Popoff, D.B. Phillips, D. Psaltis, B. Rahmani, E.R. Andresen, H. Rigneault, S. Rotter, Lei Tian, Ivo M. Vellekoop, Laura Waller, Lihong Wang,Timothy Weber, S. Xiao, C. Xu, A. Yamilov, C. Yang, Hasan Yılmaz
J. Phys. Photonics 4(4) 042501 DOI 10.1088/2515-7647/ac76f9
Energy-Efficient Iodine Uptake by a Molecular Host Guest Crystal
X. Yang, C. Li, M. Giorgi, D. Siri, X. Bugaut, B. Chatelet, D. Gigmes, A. Kermagoret, S. Brasselet, A. Martinez, D. Bardelang
Angewandte Chemie DOI: 10.1002/ange.202214039

2021

Lipids-Fluorophores Interactions Probed by Combined Nonlinear Polarized Microscopy
P. Gasecka, N. K. Balla, M. Sison, S. Brasselet
J. Phys. Chem. B 125, 13718-13729 (2021) DOI: 10.1021/acs.jpcb.1c07866
Micro-Mechanical Damages of Needle Puncture on Bovine Annulus Fibrosus Fibrils Studies using Polarisation-Resolved Second Harmonic Generation(P-SHG) Microscopy
J.-Y. Wang, J.C. Mansfield, S. Brasselet, C. Vergari, J.R. Meakin, C.P. Winlove
Journal of the Mechanical Behavior of Biomedical Materials 118, 104458 (2021) DOI 10.1016/j.jmbbm.2021.104458
Roadmap on bio-nano-photonics
Borri, Paola; Herkert, Ediz; Slesiona, Nicole; Recchia, Martina; Deckert, Thomas; Garcia-Parajo, Maria; Fantuzzi, Eric; Pruccoli, Andrea; Ragupathy, Imaiyan; Gudavicius, Dominykas; Rigneault, Herve; Majer, Jan; Zumbusch, Andreas; Munger, Eleanor; Brasselet, Sophie; Jones, Arwyn Tomos; Watson, Peter; Boppart, Stephen; Singh, Vikramdeep; Borkar, Saurabh; Quintela Rodriguez, Frank; Langbein, Wolfgang; Petropoulos, Vasilis; van Hulst, Niek F.; Maiuri, Margherita ; Cerullo, Giulio; Brida, Daniele; Troiani, Filippo; Rozzi, Carlo Andrea; Molinari, Elisa; Vengris, Mikas
Journal of Optics 23(7) 073001 DOI : 10.1088/2040-8986/abff94

2020

Cationic Biphotonic Lanthanide Luminescent Bioprobes Based on Functionalized Cross-Bridged Cyclam Macrocycles
J. Mendy, A.T. Bui, A. Roux, J.-C. Mulatier, D. Curton, A. Duperray, A. Grichine, Y. Guyot, S. Brasselet, F. Riobé, C. Andraud, B. Le Guennic, V. Patinec, R. Tripier, M. Beyler, O. Maury
ChemPhysChem 21, 10, 1036-1043 (2020) DOI: 10.1002/cphc.202000085
Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications
N. Hamon, A. Roux, M. Beyler, J.-C. Mulatier, C. Andraud, C. Nguyen, M. Maynadier, N. Bettache, A. Duperray, A. Grichine, S. Brasselet, M. Gary-Bobo, O. Maury and R. Tripier
JACS 142, 22, 10184–10197 (2020) DOI: 10.1021/jacs.0c03496
Chromato-axial memory effect through a forward-scattering slab
L Zhu, J Boutet de Monvel, P Berto, S Brasselet, S Gigan, M Guillon
Optica 7 (4), pp.338 (2020) DOI: 10.1364/OPTICA.382209
Coherent anti-Stokes Raman scattering through thick biological tissues by single wavefront shaping
M Hofer, S Shivkumar, B El Waly, S Brasselet
Phys Rev Applied 14, 024019 (2020) DOI : 10.1103/PhysRevApplied.14.024019, arXiv:2003.03761
Birefringent Fourier filtering for single molecule Coordinate and Height super-resolution Imaging with Dithering and Orientation (CHIDO)
V. Curcio, L. A. Aleman-Castaneda, T. G. Brown, S. Brasselet, M. A. Alonso
Nat. Communications 11, 5307 (2020) DOI: 10.1038/s41467-020-19064-6, arXiv:1907.05828
Brillouin microspectroscopy data of tissue-mimicking gelatin hydrogels
M. Bailey; N. Correa; S. Harding; N. Stone; S. Brasselet; F Palombo
Data in Brief 29, 105267 (2020) DOI: 10.1016/j.dib.2020.105267

2019

Label-free Nonlinear Multimodal Optical Microscopy – Basics, Development and Applications
N. Mazumder, N K. Balla, G-Y Zhuo, Y V. Kistenev, R Kumar, F-J Kao, S Brasselet, V V. Nikolaev, N A. Krivova
Frontiers in Physics Review, 31 oct 2019 DOI : 10.3389/fphy.2019.00170 (2019)
Focusing large spectral bandwidths through scattering media
A.G. Vesga, M. Hofer, N. Kumar Balla, H. B. De Aguiar, M. Guillon, S. Brasselet
Opt. Express 27 (20), 28384-28394 (2019) DOI : 10.1364/OE.27.028384. arXiv:1908.01243. Selected as Editor’s pick.
Manipulating the transmission matrix of scattering media for nonlinear imaging beyond the memory effect
M. Hofer, S. Brasselet
Opt. Letters 44(9), 2137-2140 (2019), DOI: 10.1364/OL.44.002137, arXiv:1904.10695
The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover
M.A. Juanes, D. Isnardon, A. Badache, S. Brasselet, M. Mavrakis, B. Goode
J. Cell Bio. (2019) DOI : 10.1083/jcb.201904165
Enhanced second harmonic generation of gold nanostars : optimizing multipolar radiation to improve nonlinear properties
J. Rouxel, H. Shen, N. Nguyen, S. Brasselet, T. Toury
Opt. Express 27(4), 5620-5640 (2019) DOI: 10.1364/OE.27.005620
Crystalline heterogeneity in single ferroelectric nanocrystals revealed by polarized nonlinear microscopy
C. Rendon-Barraza, F. Timpu, R. Grange, S. Brasselet
Sci. Reports 9, 1670 (2019) DOI: 10.1038/s41598-018-38229-4
Collagen reorganization in cartilage under strain probed by polarization sensitive second harmonic generation microscopy
J. Mansfield, V. Mandalia, A. Toms, C. P. Winlove, S. Brasselet
Journal of the Royal Society Interface 16 (150), pp.20180611 (2019) DOI: 10.1098/rsif.2018.0611
Image analysis applied to Brillouin images of tissue-mimicking collagen gelatins
N. Correa, S. Harding, M. Bailey, S. Brasselet, and F. Palombo
Biomed. Opt. Express 10(3), pp. 1329-1338 (2019) DOI: 10.1364/BOE.10.001329
Polarized Microscopy in the Life Sciences
S. Brasselet
Optics&Photonics News (2019) https://www.osa-opn.org/home/articles/volume_30/april_2019/features/polarization-resolved_microscopy_in_the_life_scien/. Optics and Photonics News 30(4), pp. 34-41 (2019) https://doi.org/10.1364/OPN.30.4.000034

2018

Wide field fluorescence epi-microscopy behind a scattering medium enabled by speckle correlations
M. Hofer, C. Soeller, S.Brasselet, J. Bertolotti
Opt. Express 26 (8), 9866-9881 (2018) DOI: 10.1364/OE.26.009866
Phosphatidylinositol 4,5-bisphosphate regulates the TCR/CD3 complex membrane dynamics and activation
N. Chouaki-Benmansour, K. Ruminski, A.-M. Sartre, M.-C. Phelipot, A. Salles, E. Bergot, A. Wu, G. Chicanne, M. Fallet, S. Brustlein, C. Billaudeau, A. Formisano, S. Mailfert, B. Payrastre, D. Marguet, S. Brasselet, Y. Hamon, H.T. He
Sci. Reports 8, 4966 (2018) doi.org/10.1038/s41598-018-23109-8
Effects of Excitonic Resonance on Second and Third Order Nonlinear Scattering from Few-Layer MoS2
N. K. Balla, M. O’Brien, N. McEvoy, G. S. Duesberg, H. Rigneault, S. Brasselet, D. McCloskey
ACS Photonics 5 (4), pp 1235–1240 (2018) DOI: 10.1021/acsphotonics.7b00912
Polarization resolved microscopy reveals a muscle myosin motor independent mechanism of molecular actin ordering during sarcomere maturation
O. Loison, M. Weitkunat, A. Kaya-Çopur, C. Nascimento Alves, T. Matzat, M. L. Spletter, S. Luschnig, S. Brasselet, P.-F. Lenne and F. Schnorrer
PLoS Biol 16(4): e2004718 (2018) DOI: 10.1371/journal.pbio.2004718

2017

Polarized super-resolution structural imaging inside amyloid fibrils using Thioflavine T
H. A. Shaban, C. A. Valades-Cruz, J. Savatier, S. Brasselet
Scientific Reports 7: 12482 (2017) DOI:10.1038/s41598-017-12864
Lipid Order Degradation in Autoimmune Demyelination Probed by Polarized Coherent Raman Microscopy
P. Gasecka, A. Jaouen, F.-Z. Bioud, H. Barbosa de Aguiar, J. Duboisset, P. Ferrand, H. Rigneault, N. Balla, F. Debarbieux, S. Brasselet
Biophys. J. 113(7):1520–1530
Polarization recovery through scattering media
H.B. De Aguiar, S. Gigan, S. Brasselet
Sci. Adv. 3(9):e1600743 (2017), arXiv:1511.02347
Nonlinear optical susceptibility described with a spherical formalism, applied to coherent anti-Stokes Raman scattering
C. Cleff, H. Rigneault, S. Brasselet, J. Duboisset
Phys. Rev. A (2017)
High speed polarization resolved Coherent Raman Scattering imaging
M. Hofer, N.K. Balla, S. Brasselet
Optica 4 (7), pp. 795-801 (2017). DOI : 10.1364/OPTICA.4.000795
Quantifying the polarization properties of non-depolarizing optical elements with virtual distorting elements
X. Wang, F. Yang, J. Yin, P. Ferrand, S. Brasselet
Applied Optics 56 (10) :2589 (2017)
Polarized nonlinear nanoscopy of metal nanostructures
N.K. Balla, C. Rendon-Barraza, L.M. Hoang, P. Karpinski, E. Bermudez, S. Brasselet
ACS Photonics (2017) 10.1021/acsphotonics.6b00635
Near Infrared Two photon Imaging using a Bright Cationic Yb(III) Bioprobe Spontaneously Internalized into Live Cells
A.T. Bui, M. Beyler, A. Grichine, A. Duperray, J.C. Mulatier, Y. Guyot, C. Andraud, R. Tripier, S. Brasselet, O. Maury
Chemical Communications (2017) 10.1039/C7CC02835K

2016

Enhanced nonlinear imaging through scattering media using transmission matrix based wavefront shaping
H. B. De Aguiar, S. Gigan, S. Brasselet
Phys. Rev. A, 94, 043830 (2016)
Advances in Intravital Non-Linear Optical Imaging of the Central Nervous System in Rodents
G. Rougon, S. Brasselet and F. Debarbieux
Brain Plasticity, vol. 2, no. 1, pp. 31-48, 2016, DOI: 10.3233/BPL160028
Direct imaging of molecular symmetry by coherent anti-Stokes Raman scattering
C. Cleff, A. Gasecka, P. Ferrand, H. Rigneault S. Brasselet, J. Duboisset
Nat. Communications 7, 11562 (2016)
Quantitative nanoscale imaging of orientational order in biological filaments by polarized super-resolution microscopy
C.A. Valades Cruz, H. A. Shaban, A. Kress, N. Bertaux, S. Monneret, M. Mavrakis, J. Savatier, S. Brasselet
Proc. Natl. Acad. Sci. 113 (7) E820-E828 (2016)
Detection of imprecise estimations for polarization-resolved second harmonic generation microscopy
V. Wasik, F. Galland, S. Brasselet, H. Rigneault, P. Réfrégier
J. Opt. Soc. Am. A 33(7) 1353-1362 (2016)
NIR-to-NIR Two Photon Scanning Laser Microscopy Imaging of Single Nanoparticule Doped by Yb(III) Complexes
A. Bourdolle, A. D’Aléo, C. Philippot,c P. L. Baldeck, Y. Guyot, F. Dubois, A. Ibanez, C. Andraud, S. Brasselet, O.Maury
Chem. Phys. Chem. 17(1):128-35 (2016)

2015

Unexpected Efficiency of a Luminescent Samarium(III) Complex for Combined Visible and Near-Infrared Biphotonic Microscopy
A.T. Bui, A. Grichine, S. Brasselet, A. Duperray, C. Andraud, O. Maury
Chemistry a European Journal 21 (49): 17757–17761 (2015)
In vivo evaluation of cervical stiffness evolution during induced ripening using shear wave elastography, histology and 2 photon excitation microscopy: Insight from an animal model
L. Peralta, E. Mourier, C. Richard, G. Charpigny, T. Larcher, D. Ait-Belkacem, N. K. Balla, S. Brasselet, M. Tanter, M. Muller, P. Chavatte-Palmer
PLoS One 10(8):e0133377 (2015)
Quantitative analysis of light scattering in polarization-resolved nonlinear microscopy
H. B. de Aguiar, P. Gasecka and S. Brasselet
Opt. Express 23 (7), pp. 8960-8973 (2015)
One–photon NIR sensitization of well-defined Yb(III) surface complexes for NIR–to–NIR single nanoparticle imaging
G. Lapadula, D. Trummer, M. Conley, M. Steinmann, Y.F. Ran, S. Brasselet, Y. Guyot, O. Maury, S. Decurtins, S.X. Liu, C. Coperet
Chem. Mater. 27 (6), pp 2033–2039 (2015)
Molecular orientational order probed by coherent anti-Stokes Raman scattering (CARS) and stimulated Raman Scattering (SRS) microscopy: a spectral comparative study
J. Duboisset, P. Berto, P. Gasecka, F..Z. Bioud, P. Ferrand, H. Rigneault , S. Brasselet
J. Phys. Chem. B 119 (7), pp 3242–3249 (2015)
Precision of polarization-resolved second harmonic generation microscopy limited by photon noise for samples with cylindrical symmetry
V. Wasik, P. Réfrégier, M. Roche and S. Brasselet
J. Opt. Soc. Am. A 32(8) 1437-1445 (2015)

2014

Filtering of matter symmetry properties by circularly polarized nonlinear optics
J. Duboisset, H. Rigneault, S. Brasselet
Phys. Rev. A 90, 063827 (2014)
Near-IR Two Photon Microscopy Imaging of Silica Nanoparticles Functionalized with Isolated Sensitized Yb(III) Centers
G. Lapadula, A. Bourdolle, F. Allouche, M. Conley, I. Del Rosal, L. Maron, W. Lukens, Y. Guyot, C. Andraud, S. Brasselet, C. Coperet, O. Maury, R. Andersen
Chem. Mater. 26 (2), 1062–1073 (2014)
Septins promote F-actin ring formation by cross-linking actin filaments into curved bundles
M. Mavrakis, Y. Azou-Gros, F-C. Tsai, J. Alvarado, A. Bertin, F. Iv, A. Kress, S. Brasselet, G.H. Koenderink and T. Lecuit
Nature Cell Biology 16, 322–334 (2014)
Structure of molecular packing probed by polarization-resolved nonlinear four-wave mixing and coherent anti-Stokes Raman scattering microscopy
F.-Z. Bioud, P. Gasecka, P. Ferrand, H. Rigneault, J. Duboisset, and S. Brasselet
Phys. Rev. A 89, 013836 (2014)
Ultimate use of two-photon fluorescence microscopy to map fluorophores orientational behavior
P. Ferrand, P. Gasecka, A. Kress, X. Wang, F.-Z. Bioud, J. Duboisset, S. Brasselet
Biophys. J. 106 2330–2339 (2014)

2013

Polymorphism of CMONS nanocrystals grown in silicate particles through a spray-drying process
C. Philippot J. Zimmermann, F. Dubois, M. Bacia, B. Boury, P. Baldeck, S. Brasselet, A. Ibanez
Crystal Growth and Design 13 (12), pp. 5241-5248 (2013)
Mapping the local organization of cell membranes using generalized polarization resolved confocal fluorescence microscopy
A. Kress, X. Wang, H. Ranchon, J. Savatier, H. Rigneault, P. Ferrand, S. Brasselet
Biophys. J. 105, 127-136 (2013)
Nanoscale optical properties of metal nanoparticles probed by Second Harmonic Generation microscopy
H. Shen, N. Nguyen, D. Gachet, V. Maillard, T. Toury, S. Brasselet
Opt. Express 21 (10), pp.12318-12326 (2013)
High frame-rate confocal angular resolved linear dichroism fluorescence microscopy
X. Wang, A. Kress, S. Brasselet, P. Ferrand
Rev. Sc. Instr. Rev. Sci. Instrum. 84, 053708 (2013)
Two-photon excited luminescence of lanthanide complex in monolithic sol–gel hybrid material
O. Maury, A. D'Aléo, A. Picot, S. Brasselet, P.L. Baldeck, F. Chaput, S. Parola, C. Andraud
Journal of Luminescence 133 175–179 (2013)
Thioflavine-T and Congo Red Reveal the Polymorphism of Insulin Amyloid Fibrils when Probed by Polarization-Resolved Fluorescence Microscopy
J. Duboisset, P. Ferrand, H. Wei, X. Wang, H. Rigneault, S. Brasselet
J. Phys. Chem. B 117 (3), pp 784–788 (2013)

2012

Precision increase with two orthogonal analyzers in polarization resolved second harmonic generation microscopy
P. Refregier, M. Roche, J. Duboisset, S. Brasselet
Opt. Lett. 37 (20), pp.4173-4175 (2012)
Microscopic structural study of collagen aging in isolated fibrils using polarized second harmonic generation
D. Ait-Belkacem, M. Guilbert, M. Roche, J. Duboisset, P. Ferrand, G. Sockalingum, P. Jeannesson, and S. Brasselet
J. Biomed. Opt. 17, 080506 (2012)
Polarization–resolved four-wave mixing for structural imaging in thick tissues
F. Munhoz, H. Rigneault, S. Brasselet
J. Opt. Soc. Am. B 29 (6), pp.1541-1550 (2012)
Generic model of the molecular orientational distribution probed by polarization resolved Second Harmonic Generation
J. Duboisset, Dora Aït-Belkacem, Muriel Roche, Hervé Rigneault, Sophie Brasselet
Phys. Rev. A. 85, 043829-38 (2012)
Investigation of Molecular and Protein Crystals by Three Photon Polarization Resolved Microscopy
A. Gasecka, P. Tauc, A. Bentley, S. Brasselet
Phys Rev Lett 108, 263901-05 (2012)
NIR-to-NIR Two Photon Scanning Laser Microscopy Imaging using an Ytterbium based Bioprobes
A. D’Aléo, A. Bourdolle, S. Brustlein, T. Fauquier, A. Grichine, A. Duperray, P. L. Baldeck, C. Andraud, S. Brasselet,and O. Maury
Angew. Chem. Int. Ed. 51, 6622 –6625 (2012).
Octupolar Films with Large Second Harmonic Generation and Electro-Optical Effects
M.-Y. Jeong, S. Brasselet, T.-K. Lim and B. R. Cho
Adv. Funct. Mater. 22 (4), 788–796 (2012)
Polarization resolved stimulated Raman scattering: probing depolarization ratios of liquids
F. Munhoz, S. Brustlein, R. Hostein, P. Berto, S. Brasselet and H. Rigneault
Journal of Raman Spectroscopy 43 (3), 419–424 (2012)
Advanced microscopy techniques for biological imaging
S. Monneret, S. Brasselet
Int. J. Nanotechnol. 9 (3–7), 548-566 (2012)

2011

Light-Driven Directed Motion of Azobenzene-Coated Polymer Nanoparticles in an Aqueous Medium
J.-P. Abid, Michel Frigoli, Robert Pansu, Jacob Szeftel, Joseph Zyss, Chantal Larpent, and Sophie Brasselet
Langmuir 27 (13), pp 7967–7971 (2011)
Bright luminescent silica nanoparticles for two-photon microscopy imaging via controlled formation of 4,4’-diethylaminostyryl-2,2’-bipyridine Zn(II) surface complexes”
N. Rendón, Adrien Bourdolle, Patrice L. Baldeck, Hubert Le Bozec, Chantal Andraud, Sophie Brasselet, Christophe Copéret, Olivier Maury
Chem. Mater. 23 (13), 3228–3236 (2011)
Probing orientational behavior of MHC Class I protein and lipid probes in cell membranes by fluorescence polarization-resolved imaging
A. Kress, P. Ferrand, H. Rigneault, T. Trombik, H.-T. He, D. Marguet, S. Brasselet
Biophys. J. 101, pp. 468–476 (2011)
Precision analysis in polarization-resolved second harmonic generation microscopy
P. Refregier, M. Roche, S. Brasselet
Opt. Lett. Vol. 36 (11), pp. 2149-2151 (2011)
Electro-optic effect in crystalline films of transverse planar octupolar symmetry”
M.-Y. Jeong, S. Brasselet, B. R. Cho, and T.-K. Lim
Opt. Express 19 ( 9), pp. 7979-7991 (2011)
Polarization resolved nonlinear microscopy: application to structural molecular and biological imaging
S. Brasselet
Advances in Optics and Photonics 3, pp. 205–271 (2011)
Optical Parametric Oscillators based light source for Coherent Raman Scattering microscopy: a practical overview
S. Brustlein, P. Ferrand, N. Walther, S. Brasselet, C. Billaudeau, D. Marguet, H. Rigneault
J. Biomed. Opt. Vol. 16, pp.021106 (2011)
Control of complex spectral phase profiles by single beam homodyne SPIDER
P. Schön, S. Brasselet
Opt. Lett. 36 (6), pp. 805–807 (2011)
Two-photon luminescent Eu(III) complexes embedded in silicate nanoparticles for the development of water stable bio-labels
C. Philippot, A. Bourdolle, O. Maury, F. Dubois, B. Boury, S. Brustlein, S. Brasselet, C. Andraud, A. Ibanez
J. Mater. Chem. 21, 18613-18622 (2011)

2010

Enhanced Second Harmonic Generation from individual metallic nano-apertures
P. Schön, N. Bonod, E. Devaux, J. Wenger, H. Rigneault, T. W. Ebbesen, and S. Brasselet
Optics Letters 35 (23), pp. 4063-4065 (2010)
Two-photon fluorescence correlation spectroscopy with high count rates
H. Aouani, P. Schön, S. Brasselet, H. Rigneault, J. Wenger
Biomedical Optics Express 1, pp.1075-1083 (2010)
High Order Symmetry Structural Properties of Vibrational Resonances Using Multiple-Field Polarization Coherent Anti-Stokes Raman Spectroscopy Microscopy
F. Munhoz, H. Rigneault, S. Brasselet
Phys Rev Lett. 105, 123903 (2010)
Influence of birefringence on polarization resolved nonlinear microscopy and collagen SHG structural imaging
D. Aït-Belkacem, A. Gasecka, F. Munhoz, S. Brustlein, and S. Brasselet
Opt Express 18 (14) 14859-14870 (2010)
Second Harmonic Generation microscopy in molecular crystalline nano-objects
S. Brasselet
Nonlinear Optics, Quantum Optics NLOQO 40 (1-4), pp 83-94 (2010)
Probing molecular order in zeolite L inclusion compounds using two-photon fluorescence polarimetric microscopy
A. Gasecka, L-Q. Dieu, D. Bruehviler, S. Brasselet
J. Phys. Chem. B 114 (12), pp 4192–4198 (2010)
Polarization and Phase Pulse Shaping applied to Structural Contrast in Nonlinear Microscopy Imaging
P. Schön, M. Behrndt, D. Ait-Belkacem, H. Rigneault, S. Brasselet
Phys. Rev. A 81, 013809 (2010)

2009

Synthesis and Second Harmonic Generation microscopy of nonlinear optical efficient hybrids nanoparticles embedded in polymer films. Evidence for Intra and Inter nanoparticles orientational synergy
E. Delahaye, N. Sandeau, Y. Tao, S. Brasselet, R. Clément
J. Phys. Chem. C 113 (21), pp 9092–9100 (2009)
Raman depolarization ratio of liquids probed by linear polarization Coherent Anti-Stokes Raman spectroscopy
F. Munhoz, S. Brustlein, D. Gachet, F. Billard, S. Brasselet, H. Rigneault
Journal of Raman Spectroscopy 40, (7), 775-780 (2009)
Quantitative imaging of molecular order in lipid membranes using two-photon fluorescence polarimetry
A. Gasecka, T.-J. Han, C. Favard, B.R. Cho, S. Brasselet
BioPhys J. 97 (10) 2854-2862 (2009)

2008

Polarization distortion effects in polarimetric two-photon microscopy
P. Schön, F. Munhoz, A. Gasecka, S. Brustlein, S. Brasselet
Opt. Expr. 16 (25), pp.20891-20901 (2008)
Optically induced angular motion of single molecules
G. Dutier, V. de Beaucoudrey, A. C. Mitus and S. Brasselet
Eur. Phys. Lett. 84, 67005 (2008)
Investigation of KTiOPO4 nanocrystals by means of second-harmonic light emission
Zhou C, Le Xuan L, Slablab A, Sandeau N, Brasselet S, Chauvat D, Roch JF
Chinese Optics Letters 6(1), 64-67 (2008)

2007

Defocused imaging of second harmonic generation from a single nanocrystal
N. Sandeau, L. Le Xuan, D. Chauvat, C. Zhou, J.-F. Roch, and S.Brasselet
Opt. Expr. 15 (24), 16051-60 (2007)
Octupolar Films with Significant Second-Harmonic Generation
M-Y Jeong, H.M. Kim, S.-J. Jeon, S. Brasselet, B.R. Cho
Adv. Mater. 19, 2107–2111 (2007)
Role of spatial distorsions on the quadratic nonlinear optical properties of octupolar organic and organometallic molecules
S. Bidault, S. Brasselet, J. Zyss, O. Maury, H Le Bozec
J. Chem. Phys. 126, 034312-1-13 (2007)
Nonlinear polarimetry of molecular crystals down to the nanoscale
S. Brasselet, J. Zyss
C. R. Physique 8, 165-179 (2007)

2006

Octupolar metal nanoparticles as optically driven coherently controlled nanomotors
M. Stockman, K. Li, S. Brasselet, J. Zyss
Chem. Phys. Lett. 433, 130-135 (2006)
Balanced homodyne detection in second harmonic generation microscopy
L. Le Xuan, F. Marquier, D. Chauvat, S. Brasselet, F. Treussart, S. Perruchas, C. Tard, T. Gacoin, JF Roch
Appl. Phys. Lett. 89, 121118 (2006)
Second harmonic generation from individual hybrid MnPS3-based nanoparticles investigated by nonlinear microscopy
E. Delahaye, N. Tancrez, T. Yi, I. Ledoux, J. Zyss, S. Brasselet, R. Clément
Chem. Phys. Lett. 429, 533-537 (2006)
Electro-optical microscopy: mapping nonlinear polymer films with micrometric resolution
T. Toury, S. Brasselet, J. Zyss
Opt. Lett. 31 (10), 1468-1471 (2006)
Optically Tunable Nonlinearities in Polymers Based on Photoisomerizable Metal-Based Coordination Complexes
S. Bidault, L. Viau, O. Maury, S. Brasselet, J. Zyss, E. Ishow, K. Nakatani, H Le Bozec
Adv Func Mater 16 (17), 2252-2262 (2006)

2005

Nanometric scale investigation of the nonlinear efficiency of perhydrotriphynylene inclusion compounds
K. Komorowska, S. Brasselet, J. Zyss, L. Pourlsen, M. Jazdzyk, H.J. Egelhaaf, J. Gierschner, M. Hanack
Chem. Phys. 318 (1-2), 12-20 (2005)
Local orientational distribution of molecular monolayers probed by nonlinear microscopy
C. Anceau, S. Brasselet, J. Zyss
Chem. Phys. Lett. 411(1-3), 98-102 (2005)
Matching molecular and optical multipoles in photoizomerizable octupolar nonlinear systems
R. Piron, S. Brasselet, D. Josse, J. Zyss, G. Viscardi
J. Opt. Soc. Am. B 22 (6) 1276-1282 (2005)
Encoding multipolar polarization patterns by optical poling in polymers: towards nonlinear optical memories
S. Bidault, J. Gouya, S. Brasselet, J. Zyss
Opt. Expr. 13 (2) 506-510 (2005)
High efficiency and quadratic nonlinear optical properties of a fully optimized 2-D octupolar crystal by nonlinear microscopy
V. Le Floc’h, S. Brasselet, J. Zyss, B.R. Cho, S.H. Lee, S.J. Jeon, M. Cho, K.S. Min, M.P. Suh
Adv. Mater. 17 (2) 196-200 (2005)

2004

All optical orientation of photoisomerizable octupolar zinc(II) complexes in polymer films
L. Viau, S. Bidault, O. Maury, S. Brasselet, I. Ledoux, J. Zyss, E. Ishow, K. Nakatani, H. Le Bozec
J. Am. Chem. Soc. 126, 8386-8387 (2004)
Influence of the excitation transfer on the all-optical orientation of fluorescent chromophores in polymers
S. Bidault, S. Brasselet, V. Le Floc’h, J. Zyss
Nonlinear Optics and Quantum Optics 31 (1-4), 203-220 (2004)
Enhanced second harmonic generation by nanorough metal surfaces : nanoscale dephasing, depolarization, and correlations
M.I. Stockman, D.J. Bergman, C. Anceau, S. Brasselet, J. Zyss
Phys. Rev. Lett. 92(5), 057402 (2004)
Coherent control of the optical nonlinear and luminescence anisotropies of molecular thin films by multiphoton excitations
S. Bidault, S. Brasselet, J. Zyss
Opt. Lett. 29(11), 1242-1244 (2004)
In situ diagnostics of the crystalline nature of single organic nanocrystals by nonlinear microscopy
S. Brasselet, V. Le Floc’h, F. Treussart, J.F. Roch, J. Zyss, E. Botzung-Appert, A. Ibanez
Phys. Rev. Lett. 92(20), 207401 (2004)

2003

Monitoring of orientation in molecular ensembles by polarization sensitive nonlinear microscopy
V. Le Floc’h, S. Brasselet, J.F. Roch, J. Zyss
J. Phys. Chem. B 107, 12403-12410 (2003)
Local second harmonic generation enhancement on gold nanostructures probed by 2-photon microscopy
C. Anceau, S. Brasselet, P. Gadenne, J. Zyss
Opt. Lett 83, 2681-2692 (2003)

2002

Photoinduced multipolar tensorial patterning in polymer films by coherent control of molecular orientation
S. Brasselet, S. Bidault, J. Zyss
C.R. Acad. Sci. Physique (Paris) t. 3, n° 4, 479 (2002)
Translational diffusion of individual Class II MHC membrane proteins in cells
M. Vrlijc, S.Y. Nishimura, S. Brasselet, W.E. Moerner, H. McConnell
Biophys. J. 83, 2681-2692 (2002)

2001

Molecular engineering of octupolar tris(bipyridyl) metal complexes
H. LeBozec, T. Renouard, M. Bourgault, C. Dhenaut, S. Brasselet, I. Ledoux, J. Zyss
Synthetic Metals 214, 185-189 (2001)

2000

Polymer microcavity with photoencoded quadratic nonlinearity
R. Piron, E. Toussaere, D. Josse, S. Brasselet, J. Zyss
Optics Letters 25(17), (2000)
Towards nonlinear photonics in all-optically poled polymer microcavities
R. Piron, E. Toussaere, D. Josse, S. Brasselet, J. Zyss
Synthetic Metals 115, 109 (2000)
Nonlinear photonic engineering : from NLO as a goal to NLO as a tool
J. Zyss, S. Brasselet
C. R. Acad. Sci. Paris t. 1, Série IV, 601-608 (2000)
Fluorescence Behavior of Single-Molecule pH-sensors
S. Brasselet, W.E. Moerner
Single Mol. 1(1), 15 (2000)
Single Molecule Resonant Energy Transfer in Calcium-Dependent Cameleon
S. Brasselet, E.J.G. Peterman, A. Miyawaki, W.E. Moerner
J. Phys. Chem. B 104(15), 3676 (2000)
Noncentrosymmetric Triazolephtalocyanines as second order nonlinear optical materials
G. Rojo, F. Agullo-Lopez, B. Cabezon, T. Torres, S. Brasselet, I. Ledoux and J. Zyss
J. Phys. Chem. B. 104, 4295-4299 (2000)

1999

The Fluorescence Dynamics of Single Molecules of Green Fluorescent Protein
E.J.G. Peterman, S. Brasselet, W.E. Moerner
J. Phys. Chem. A 103(49), 10553 (1999)
Optical methods for exploring dynamics of single copies of green fluorescent proteins
W.E. Moerner, E.J.G. Peterman, S. Brasselet, S. Kummer and R.M. Dickson
Cytometry 36(3), 232 (1999)
New octupolar star-shaped molecular structures for quadratic nonlinear optics
S. Brasselet, F. Cherioux, P. Audebert and J. Zyss
Chem. Mater. 11(7), 1915 (1999)
Tetrahedral bipyridyl copper(I) complexes : a new class of non-dipolar chromophore for nonlinear optics
T. Renouard, H. LeBozec, S. Brasselet, I. Ledoux, J. Zyss
Chem. Comm. 10, 871 (1999)
Steering non-centrosymmetry into the third dimension : crystal engineering of an octupolar nonlinear optical crystal
V.R. Thalladi, R. Boese, S. Brasselet, I. Ledoux, J. Zyss, R.K.R. Jetti, G.R. Desiraju
Chem. Comm. 17, 1639 (1999)

1998

Multipolar molecules and multipolar fields: probing and controlling the tensorial nature of nonlinear molecular media
S. Brasselet and J. Zyss
J. Opt. Soc. Am. B feature issue on Organic and Polymeric Nonlinear Optical Materials 15 (1), 257 (1998)
Design and synthesis of new octupolar molecules for second harmonic generation
O. Riant, G. Bluet, S. Brasselet, N. Druze, I. Ledoux, F. Lefloch, A. Skibniewski and J. Zyss
Mol. Cryst. Liq. Cryst. 322, 35 (1998)
Synthesis, nonlinear optical, photophysical and electrodynamical properties of subphtalocyanines
B. Del Rey, U. Keller, T. Torres, G. Rojo, F. Agullo-Lopez, S. Nonell, C. Marti, S. Brasselet, I. Ledoux and J. Zyss
J. Am. Chem. Soc. 120(49), 12808 (1998)
Octupolar versus dipolar crystalline structures in nonlinear optics. A dual crystal and propagative engineering approach
J. Zyss, S. Brasselet, V. Thalladi and G. Desiraju
J. Chem. Phys. 109 (2), 658 (1998)
Crystal engineering of some 2,4,6-triaryloxy-1,3,5-triazines : Octupolar nonlinear materials
V.R. Thalladi, S. Brasselet, H.C. Weiss, D. Bläser, A.K. Katz, H.L. Carrell, R. Boese, J. Zyss, A. Nangia, G.R. Desiraju
J. Am. Chem. Soc. 120(11), 2563 (1998)

1997

Control of the polarization dependence of optically poled nonlinear polymer films
S. Brasselet and J. Zyss
Opt. Lett. 22(19), 1464 (1997)
Engineering of an octupolar nonlinear optical crystal : tribenzyl isocyanurate
V.R. Thalladi, S. Brasselet, D. Bläser, R. Boese, J. Zyss, A. Nangia, G.R. Desiraju
Chem. Comm. 19, 1841 (1997)
Design, characterization and processing of hybrid organic-inorganic coatings with very high second-order optical nonlinearities
B. Lebeau, S. Brasselet, J. Zyss and C. Sanchez
Chem. Mater. 9(4), 1012 (1997)

1996

[n]-Polyenovanillins as New Push-Pull Polyenes for Nonlinear Optics: Synthesis, Experimental and Theoretical Investigation of their Spectroscopic Properties, Electronic Structures, and Quadratic Hyperpolarizabilities
T. Brotin, C. Andraud, I. Ledoux, S. Brasselet, J. Zyss, M. Perrin, A. Thozet and A. Chollet
Chem. Mater. 8, 890 (1996)
Subphtalocyanines: Novel Targets for Remarkable Second Order Optical Nonlinearities
A. Sastre, T. Torres, M.A. Diaz-Garcia, F. Agullo-Lopez, C. Dhenaut, S. Brasselet, I. Ledoux and J. Zyss
J. Am. Chem. Soc. 118(11), 2746 (1996)
Large Second-order Nonlinearities in Azo dyes Grafted Hybrid Sol-Gel Coatings
B. Lebeau, C. Sanchez, S. Brasselet, J. Zyss, G. Froc, M. Dumont
New J. Chem. 20(1), 13 (1996)
Two Photon Rayleigh Scattering in Micellar and Microemulsion Systems
M. Paillette, S. Brasselet, I. Ledoux and J. Zyss
Progr. Colloïd Polym. Sci. 100, 68, (1996)