Post-doctoral position for the development of nonlinear microscopy in the (...)

Post-doctoral position for the development of nonlinear microscopy in the field of cancer diagnostics

Accueil › Recrutement › Post-doctoral position for the development of nonlinear microscopy in the (...)

Funding : ERC Consolidators grant

Duration : 36-month – Starting date September 2024

Salary : ≥ 2800€ negotiable

Supervisor : Dr. Sandro Heuke, Chargé de Recherche at the CNRS

Research team : MOSAIC

Address : Institut Fresnel, Av Escadrille Normandie-Niémen, 13397 Marseille Cedex 20, France.

Our mission
Our rent advances in coherent Raman microscopy allow for the real-time generation of artificially stained images of cancer samples which previously required time-consuming histopathological staining procedures. These images serve as feedback for surgeons to guide cancer surgery. As the main challenge, the examination of thick cancer samples is currently impossible, as all excitation light in coherent Raman microscopy is scattered forward and must pass through the sample. Within this project, you will develop a new coherent Raman technique called coherent Stokes Raman scattering (CSRS) microscopy. As the game-changer, CSRS will send the signal photons directly into the backward direction and, therefore, enable the investigation of thick, non-transparent cancer samples. Moreover, we will use CSRS’ backscattering property to record the CSRS spectrum of tissue at unprecedented speed levels using novel spectrometer concepts and multi-focus or wide-field illumination approaches. From these CSRS spectra, a precise diagnosis of the cancerous tissue will be derived by machine learning algorithm. Your mission is to set up and characterize these novel microscopy techniques and evaluate their functionality on cancer tissue.

Your Profile

Attitude : For you, research is a vocation and not just a source of income. High levels of initiative, creativity and curiosity are expected from you.

Willingness to perform:During university education you were always in the top 25% and you should have at least 2 major publications as first author.

Qualification:You have completed a degree in the field of photonics, e.g. physics, physical chemistry or similar. You have developed microscopy techniques or other imaging methods during your doctorate.

Curious ? Please send a letter of motivation, a detailed CV, a reference letter and 3 academic references to Sandro.Heuke@fresnel.fr.