In vivo studies of biomineralization by nonlinear coherent Raman optical microscopy

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Description : The thesis will take place at the Fresnel Institute, on the Saint Jérôme campus. The student
will join
the Mosaic team, in collaboration with the Comix team, the IFREMER group in Montpellier and the
Monaco Scientific Center. During the thesis, the student will have to develop the experimental
coherent Raman microscopy experimental device adapted to the constraints of in vivo observation.
Live animals will be received in the laboratory and raised in the aquarium at the Institute. The
objective of the thesis is to develop the protocol allowing the in vivo imaging of the calcifying tissue
of the living animals, to conduct the first in vivo biomineralization experiments and to compare the
observations with the literature in order to propose an interpretation of the results.

Laboratory : Institut Fresnel, CNRS, Marseille

Thesis supervisor : Duboisset Julien (HDR)

Co-supervisor : Chamard Virginie (HDR)

Email : julien.duboisset@fresnel.fr virginie.chamard@fresnel.fr

Adress : Institut Fresnel, Domaine Universitaire de Saint Jérôme, 13397 Marseille, France

Tel : +33 413945482