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Photoacoustic imaging

Principal investigator: Thomas Chaigne

There is currently no technique to image neuronal activity with cellular resolution (∼ 10 µm), with large fields of view (∼ 1 cm ) deep inside the brain (> 1 mm), while resolving single action potentials (∼ 1 ms).
Most efforts are devoted to scaling up multi-photon fluorescence microscopy to image increasingly larger and deeper populations of neurons, but these techniques are inherently limited by light scattering to shallow depths.
We are developing photoacoustic imaging techniques to bypass this issue.
More soon…