Xavier Audier, Ph.D.

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Xavier AUDIER will defend his PhD thesis "Fast Stimulated Raman Spectroscopy and spectral imaging" on thurdsday, december 13 at 10:00 a.m. in Rouard amphitheater, Campus St Jérôme, Marseille.

The jury will be composed of :

- Randy A Bartels, Professor at Colorado State University (rapporteur)
- Thomas R Huser, Professor at Bielefeld University (rapporteur)
- Nicolas Forget, Ph.D., R&D Group Manager at FASTLITE
- Sophie Brasselet, Directrice de Recherche CNRS
- Hervé Rigneault, Directeur de Recherche CNRS (thesis director)

Abstract :
Combining microscopy and spectroscopy, one can achieve spectrally resolved imaging, and provide a solution to various chemical, biological, or medical challenges.
Coherent Raman Scattering (CRS) has proven extremely valuable in providing chemical information, with a higher resolution and shorter acquisition time than spontaneous Raman scattering.
The acquisition rate of the spectral information from a sample remains the limiting factor of CRS imaging, and several experimental schemes are being investigated to push the technology toward higher imaging frame rates.
This work develops one such scheme.
Combining Stimulated Raman Scattering (a CRS technique), spectral focusing of chirped pulses, and a fast acousto-optic delay line, we achieved unprecedented spectral acquisition rates.
The theoretical, technological, and engineering frameworks enabling such acquisition are described in details.
The application to pharmaceutical quality control, time resolved chemical transformations, biology, and histology is demonstrated.