Biologie
Accueil › Recherche › Imagerie › Biologie › New fiber probes Lensless endoscope
New fiber probes Lensless endoscope
for biosensing and imaging
Principal investigator : Hervé Rigneault
keywords : nonlinear endoscope, lensless endoscope, wavefront shaping, micro-structured optical fibers, Raman probes
We are interested in extending molecular spectroscopy and nonlinear imaging through flexible fiber probes and endoscopes. Using specially design micro-structured fibers, we are investigating
- (1) the use of hollow core photonic crystal fibers for flexible nonlinear imaging endoscopes and Raman probes.
- (2)the use of multicore and multimode fibers combined with wavefront shaping for lensless nonlinear imaging endoscope.
Hollow core photonic crystal fiber for flexible nonlinear imaging endoscopes and Raman probes.
Delivering ultra-short laser pulses through fiber optics is limited by the nonlinear interactions (SPM, FWM, Raman) in the silica fiber core that affect the pulse spectral and time profiles. Here we are using specially designed band gap and Kagome lattice hollow core fibers to deliver ultra-short pulses at the fiber distal end, taking advantage of the ultra-low nonlinearity of the air core. These fibers also feature a double silica clad for optimal nonlinear and Raman signal back collection.
Lensless endoscope
We are combining wavefront shaping with multicore or multimode fibers to perform distal beam scanning imaging without the use of any distal optics. This produce imaging endoscope with diameters as small as few hundreds of microns fully compatible with nonlinear imaging.
Nonlinear flexible endoscopes and distal Raman probes are used to address :
- Deep brain imaging and neuron network activity in living mice (neurobiology)
- Deep tissue morphology
- Deep tissue Raman spectroscopy
Publications
2023
N. Gajendra Kumar, S. Sivankutty, V. Tsvirkun, A. Cassez, D. Labat, R. Cossart, G. Bouwmans, E. R. Andresen, and H. Rigneault
Optics Express 31, 15334-15341 (2023).
doi.org/10.1364/OE.485550
Z. Lyu, K. Abrashitova, J. F. de Boer, E. R. Andresen, H. Rigneault, and L. V. Amitonova
Optics Express 31, 11249-11260 (2023)
opg.optica.org/oe/abstract.cfm ?uri=oe-31-7-11249
2022
F. El Moussawi, M. Hofer, D. Labat, A. Cassez, G. Bouwmans, S. Sivankutty, R. Cossart, O. Vanvincq, H. Rigneault, and E. R. Andresen
ACS Photonics 30, 25020 (2022)
https://doi.org/10.1021/acsphotonics.2c00661
D. Septier, V. Mytskaniuk, R. Habert, D. Labat, K. Baudelle, A. Cassez, G. Brévalle-Wasilewski, M. Conforti, G. Bouwmans, H. Rigneault, and A. Kudlinski
Optics Express 30, 25020-25033 (2022)
https://doi.org/10.1364/OE.462361
S. Guérit, S. Sivankutty, J. Lee, H. Rigneault, and L. Jacques,
SIAM Journal on Imaging Sciences 15, 387-423 (2022)
doi.org/10.1137/21M1407586
2021
S. Sivankutty, A. Bertoncini, V. Tsvirkun, N. Gajendra Kumar, G. Brévalle, G. Bouwmans, E. R. Andresen, C. Liberale, and H. Rigneault
Optics Letters 46, 4968-4971 (2021)
2020
A. Kudlinski, A. Cassez, O. Vanvincq, D. Septier, A. Pastre, R. Habert, K. Baudelle, M. Douay, V. Mytskaniuk, V. Tsvirkun, H. Rigneault, and G. Bouwmans
Optics Express 28, 15062-15070 (2020) doi.org/10.1364/OE.389084
2019
V. Tsvirkun, S. Sivankutty, K. Baudelle, R. Habert, G. Bouwmans, O. Vanvincq, E. R. Andresen, and H. Rigneault
Optica 6, 1185-1189 (2019)
2018
S. Sivankutty, V. Tsvirkun, G. Bouwmans, E. R. Andresen, D. Oron, H. Rigneault, and M. A. Alonso
Optics Letters 43, 4493-4496 (2018)
S. Sivankutty, V. Tsvirkun, O. Vanvincq, G. Bouwmans, E. R. Andresen, and H. Rigneault
Optics Letters 43, 3638-3641 (2018)
2017
V. Tsvirkun, S. Sivankutty, G. Bouwmans, O. Vanvincq, E. R. Andresen, and H. Rigneault
Optics Express 25, 31863-31875 (2017)
A. Lombardini, E. R. Andresen, A. Kudlinski, I. Rimke, and H. Rigneault
Optics Letters 42, 1824-1827 (2017)
D. Kogan, S. Sivankutty, V. Tsirkun, G. Bouwmans, E. R. Andresen, H. Rigneault, D. Oron
Optics Letters 42, 647-650 (2017)
2016
V. Tsvirkun, S. Sivankutty, G. Bouwmans, O. Katz, E. R. Andresen, and H. Rigneault
Optics Letters 41, 4771 (2016)
Esben Ravn Andresen, Siddharth Sivankutty, Viktor Tsvirkun, Géraud Bouwmans, Hervé Rigneault
J. Biomedical Optics 21, 121506 (2016)
S. Sivankutty, V. Tsvirkun, G. Bouwmans, D. Kogan, D. Oron, E. R. Andresen, and H. Rigneault
Optics Letters 41, 3531-3534 (2016)
A. Porat, E. R. Andresen, H. Rigneault, D. Oron, S. Gigan, and O. Katz
Optics Express 24, 16835-16855 (2016)
S. Sivankutty, E. R. Andresen, G. Bouwmans, T. G. Brown, M. A. Alonso, H. Rigneault
Optics Letters 41, 2105-2108 (2016)
S. Sivankutty, E. R. Andresen, R. Cossart, G. Bouwmans, S. Monneret, H. Rigneault
Optics Express 24, 825 (2016)
2015
E. R. Andresen, S. Sivankutty, G. Bouwmans, L. Gallais, S. Monneret, and H. Rigneault
J. Opt. Soc. Am. B 32, 1221-1228 (2015)
2013
E. Andresen, G. Bouwmans, S. Monneret, H. Rigneault
Optics Express 21, 20713-20721 (2013)
E. R. Andresen, G. Bouwmans, S. Monneret, and H. Rigneault
Optics Letters 38, 609-611 (2013)
2012
P. Ghenuche, H. Rigneault and J. Wenger
Optics Express 20, 28370-28387 (2012)
P. Ghenuche, S. Rammler, N. Y. Joly, M. Scharrer, M. Frosz, J. Wenger, P. St. J. Russell, and H. Rigneault
Optics Letters 37, 4371–4373 (2012)
2011
S. Brustlein, P. Berto, R. Hostein, P. Ferrand, C. Billaudeau, D. Marguet, A. Muir, J. Knight, H. Rigneault
Optics Express 19, 12562 – 12568 (2011)